糖尿病口服降糖药分类_鍙ｆ湇闄嶇硸鑽不鐤楁柊璇婃柇鐨?鍨嬬硸灏跨梾鐤楁晥瑙傚療
时间：2019-01-14 04:44:02 来源：达达文档网 本文已影响 人 
銆€銆€銆愭憳瑕併€?鐩殑 瑙傚療鍙ｆ湇闄嶇硸鑽鏂拌瘖鏂殑2鍨嬬硸灏跨梾鐨勭枟鏁堛€傛柟娉?35渚嬫柊璇婃柇鐨?鍨嬬硸灏跨梾鎮ｈ€咃紝缁欎簣鏍煎垪缇庤劜鍙婇樋鍗℃尝绯栧彛鏈嶏紝瑙傚療鏈嶈嵂鍚庤绯栬揪鏍囨椂闂淬€傜粨鏋?娌荤枟1鍛ㄥ悗琛€绯栨槑鏄句笅闄嶏紝2鍛ㄨ绯栬揪鏍囷紝1涓湀闄嶇硸鑽墿寮€濮嬪噺閲忥紝3涓湀鍚庢湁6渚嬫偅鑰呭仠鏈嶆墍鏈夐檷绯栬嵂鐗┿€傜粨璁?鏍煎垪缇庤劜(浜氳帿鍒?涓庨樋鍗℃尝绯?鎷滅硸骞?鑱斿悎搴旂敤鍙槑鏄炬敼鍠勯珮琛€绯栫姸鎬併€?
銆€銆€銆愬叧閿瘝銆?2鍨嬬硸灏跨梾锛涙牸鍒楃編鑴?浜氳帿鍒?;闃垮崱娉㈢硸(鎷滅硸骞?
銆€銆€
銆€銆€Evaluating the effect of treatments with oral antidiabetic drugs in newly diagnosed type 2 diabetic patients
銆€銆€
銆€銆€銆怉bstract銆?Objective To evaluate the effect of oral antidiabetic grugs in newly diagnosed type 2 diabetic patients. Methods Thirty-five newly dignosed type 2 diabetic patients were treated by Glimepiride and acarbose, evaluated the time of blood glucose reaching the standards after treatments. Results Blood glucose were dramatically decreased aftger 1 week treatments and reached the standards after 2 weeks treatments.The doses of the oral antidiabetic drugs began to decrease after 1 month and 6 cased of patients were stopped using all the oral antidiabetic drugs after 3 months. Conclusion Combination of Glimepiride(Amaryl) and Acarbose(Glucobay) can improve the state of hyperglycaemia dramatically.
銆€銆€銆怟ey words銆?Type 2 diabetic patients锛汫limepiride (Amaryl)锛汚carbose(Glucobay)
銆€銆€
銆€銆€绯栧翱鐥呯殑鍙戠梾鐜囦笉鏂鍔狅紝绯栧翱鐥呯殑鎬ユ參鎬у苟鍙戠棁鍧囦弗閲嶅▉鑳佺潃浜轰滑鐨勫仴搴凤紝褰卞搷鐫€浜轰滑鐨勭敓瀛樿川閲忋€備弗鏍兼帶鍒惰绯栦娇鍏惰揪鍒扮悊鎯虫按骞冲彲棰勯槻鍜屽噺灏戝悇绉嶅苟鍙戠棁鐨勫彂鐢燂蓟1锛姐€? 鍨嬬硸灏跨梾鐨勭梾鐞嗙敓鐞嗗熀纭€涓鸿儼宀涚礌鎶垫姉鍜岃儼宀涚礌鍒嗘硨涓嶈冻锛岃€屾寔缁珮琛€绯栨墍鑷寸硸姣掓€ф槸閫犳垚尾缁嗚優鍔熻兘杩涜鎬т笅闄嶏紝鑳板矝绱犳姷鎶楃殑閲嶈鍥犵礌锛?锛姐€傝繎骞存潵鐨勭爺绌惰瘉鏄庯紝瀵瑰垵璇婃柇鐨?鍨嬬硸灏跨梾锛屽敖鏃╂帶鍒惰绯栵紝瑙ｉ櫎楂樼硸姣掓€э紝鍙仮澶嶈儼宀涳饥缁嗚優鍔熻兘锛?锛姐€傜洰鍓嶅鍒濊瘖鏂殑2鍨嬬硸灏跨梾鎮ｈ€呮櫘閬嶄娇鐢ㄨ儼宀涚礌寮哄寲娌荤枟浠ユ敼鍠勯珮琛€绯栫姸鎬併€傝€屽浜庝笉鎰挎剰鎺ュ彈鑳板矝绱犳不鐤楃殑鍒濊瘖鎮ｈ€呯殑娌荤枟鎶ラ亾涓嶅锛屾垜浠湪闂ㄨ瘖瀵?5渚嬩笉鎰挎帴鍙楄儼宀涚礌寮哄寲娌荤枟鐨勬柊璇婃柇2鍨嬬硸灏挎偅鑰呯粰鍙ｆ湇闄嶇硸鑽墿娌荤枟锛屽彇寰椾簡涓€瀹氱枟鏁堬紝鐜版姤鍛婂涓嬨€?
銆€銆€1 璧勬枡涓庢柟娉?
銆€銆€1.1 涓€鑸祫鏂?鏂拌瘖鏂殑2鍨嬬硸灏跨梾鎮ｈ€?5渚嬶紝绗﹀悎WHO1999绯栧翱鐥呰瘖鏂爣鍑嗭紝鍏朵腑鐢?9渚嬶紝濂?6渚嬶紝骞冲潎骞撮緞(41卤9)宀侊紝鎵€鏈夋偅鑰呯殑绌鸿吂琛€绯?10 mmol/L,椁愬悗2 h琛€绯?15 mmol/L,涓嶅悎骞剁硸灏跨梾鎬ユ參鎬у苟鍙戠棁锛屾湭鏈嶇敤浠讳綍闄嶇硸鑽墿鍙婅儼宀涚礌娌荤枟銆?
銆€銆€1.2 鏂规硶 瀵规墍鏈夋偅鑰呰繘琛岀硸灏跨梾鏁欒偛锛屽埗瀹氬悎鐞嗛ギ椋熷強杩愬姩鏂规锛屽苟鍧氭寔鍦ㄩ棬璇婃娴嬭绯栬嚦灏戞瘡鍛?娆?涓夐鍓嶆垨涓夐鍚?锛屼笌鍖荤敓瀵嗗垏鑱旂郴锛岃瀵熻绯栬揪鏍囨椂闂达紝鐢ㄨ嵂鍓傞噺銆?
銆€銆€1.3 鑽墿 鍏ㄩ儴鎮ｈ€呭潎缁欎簣鏍煎垪缇庤劜(浜氳帿鍒?鍙婇樋鍗℃尝绯?鎷滅硸骞?鍙ｆ湇锛屾牴鎹绯栧€艰皟鏁撮檷绯栬嵂鍓傞噺銆備簹鑾埄鏈€澶у墏閲? mg锛?娆?d鍙ｆ湇锛屾渶灏忓墏閲? mg锛?娆?d鍙ｆ湇锛涙嫓绯栧钩鏈€澶у墏閲?0 mg锛屼竴鏃ヤ笁娆★紝椁愭椂鍙ｆ湇锛屾渶灏忓墏閲?5 mg锛屾瘡鏃ヤ笁娆★紝椁愭椂鍙ｆ湇銆?
銆€銆€1.4 琛€绯栫洃娴?鎵€鏈夋偅鑰呭潎浣跨敤寰峰浗缃楁皬琛€绯栨祴璇曚华妫€娴嬫墜鎸囨湯姊㈣鐨勮绯栵紝瑙傚療娌荤枟鍓嶅悗琛€绯栧彉鍖栥€?
銆€銆€1.5 鐤楁晥鍒ゆ柇鎸囨爣 浠ョ┖鑵硅绯?.0~6.0 mmol/L锛岄鍚?.5~8.0 mmol/L涓鸿绯栨帶鍒剁洰鏍囷紝鏍规嵁琛€绯栧€艰皟鏁撮檷绯栬嵂鐢ㄩ噺锛岀洿鑷宠绯栬揪鏍囷紝闅忚鍗婂勾锛岃瀵熺┖鑵癸紝椁愬悗2 h琛€绯栨按骞冲強绯栧寲琛€绾㈣泲鐧藉€笺€傛牴鎹绯栧彉鍖栨儏鍐佃繘琛屼笉鍚岀殑澶勭悊銆?
銆€銆€1.6 缁熻瀛︽柟娉?璁￠噺璧勬枡浠ワ紙x卤s锛夎〃绀猴紝缁勯棿姣旇緝鐢╰妫€楠岋紝鎵€鏈夌殑缁熻瀛﹁绠楀湪SPSS 10.0杞欢澶勭悊锛孭锛?锛斤紝鑰屽鑷村姛鑳借繘琛屾€ц“閫€鐨勫師鍥犲垯鏄敱浜庢寔缁瓨鍦ㄧ殑鑳板矝绱犳姷鎶楀姞涓婄硸姣掓€у拰鑴傛瘨鎬у鑳板矝尾缁嗚優鍔熻兘涓嶆柇鎹熶激锛屽叾涓珮琛€绯栦负璇卞彂鍜屽姞閲嶄笂杩板彉鍖栫殑鏈€閲嶈鍥犵礌銆傚湪绯栧翱鐥呮棭鏈燂紝尾缁嗚優鍔熻兘鎹熷鏄彲閫嗙殑锛岃В闄ら珮琛€绯栨瘨鎬у彲浣胯儼宀浳茬粏鑳炰紤鎭紝鏀瑰杽鏃╂湡鑳板矝绱犲垎娉岀己闄凤紝淇濇姢鑳板矝鍔熻兘鎴愪负绯栧翱鐥呮不鐤楃殑閲嶇偣锛?锛姐€傝€屼簹鑾埄鍏锋湁鍙岄噸浣滅敤鏈哄埗锛屼笉浠呬績杩涜儼宀涚礌鍒嗘硨锛屽苟鏀瑰杽鑳板矝绱犳姷鎶楋紝鑰屼簹鑾埄淇冧娇鑳板矝绱犲垎娉岀殑浣滅敤鏄緷璧栦簬琛€绯栨按骞崇殑淇冭儼宀涚礌鍒嗘硨銆傚綋钁¤悇绯栨祿搴﹀楂樻椂锛屼簹鑾埄淇冭繘鑳板矝绱犲垎娉屽鍔狅紝浠庤€屾湁鏁堝湴闄嶄綆琛€绯栵紝褰撹憽钀勭硸娴撳害闄嶄綆鏃讹紝浜氳帿鍒╀績鑳板矝绱犲垎娉岀浉搴斿噺灏戯紝鍗冲悓鏍风殑闄嶇硸浣滅敤锛屾洿灏戠殑鑳板矝绱犲垎娉岋紝鑺傜渷鑳板矝绱犵殑閲婃斁锛屼繚鎶よ儼宀浳茬粏鑳烇紝鍙︿簹鑾埄杩樺叿鏈夋洿鏄捐憲鐨勮儼澶栭檷绯栨椿鎬э紝鏄捐憲鏀瑰杽鑳板矝绱犳姷鎶楋紝澧炲姞澶栧懆缁勭粐瀵硅儼宀涚礌鐨勬晱鎰熸€с€傝€屾嫓绯栧钩涓何?钁¤悇绯栬嫹閰舵姂鍒跺墏锛屽湪灏忚偁榛忚啘鍒风姸缂樼珵浜夋€ф姂鍒惰憽钀勭硸娣€绮夐叾锛岃敆绯栭叾锛岄害鑺界硸閰跺拰寮傞害鑺界硸閰讹紝寤剁紦钁¤悇绯栧拰鏋滅硸绛夌殑鍚告敹锛屽彲闄嶄綆椁愬悗琛€绯栥€備粠浠ヤ笂缁撴灉鏉ョ湅锛屼簩鑽仈鍚堝簲鐢紝鍙栧緱浜嗕竴瀹氱枟鏁堛€?
銆€銆€鍙?鑰?鏂?鐚?
銆€銆€锛?锛?鏉庝竴鍚涳紝姣嶄箟鏄?鑳板矝绱犳车娌荤枟鍜屽姩鎬佽绯栫洃娴嬬殑涓村簥搴旂敤.涓浗瀹炵敤鍐呯鏉傚織,2007锛?7(7)锛?02.
銆€銆€锛?锛?鐜嬪悏鑰€.鍐呯瀛?鍖椾含锛氫汉姘戝崼鐢熷嚭鐗堢ぞ锛?001锛?76.
銆€銆€锛?锛?绾珛鍐?鈥溛茬粏鑳炰紤鎭€濇蹇靛強鍏跺湪绯栧翱鐥呴槻娌讳腑鐨勫簲鐢?鍥藉鍖诲鍐呭垎娉屽鍒嗗唽锛?003锛?3(3)锛?1.
銆€銆€锛?锛?缈佸缓骞?尾缁嗚優鍔熻兘涓?鍨嬬硸灏跨梾鐨勯闃插拰娌荤枟.鍥藉鍖诲鍐呭垎娉屽鍒嗗唽,2003锛?3(3)锛?82.
銆€銆€锛?锛?鐜嬮湝.鑳板矝绱犲己鍖栨不鐤楀垵鍙?鍨嬬硸灏跨梾鐨勭枟鏁?瀹炵敤鍖诲鏉傚織,2006,23(11)锛?298.
銆€銆€娉細鏈枃涓墍娑夊強鍒扮殑鍥捐〃銆佹敞瑙ｃ€佸叕寮忕瓑鍐呭璇蜂互PDF鏍煎紡闃呰鍘熸枃
鏈枃涓哄叏鏂囧師璨?鏈畨瑁匬DF娴忚鍣ㄧ敤鎴疯鍏堜笅杞藉畨瑁?鍘熺増鍏ㄦ枃
